Alumni News

The Dept. of of Natural Resources and Environmental Management invites you to tune in, sit back, and enjoy the 494 Senior Capstone Project Presentations:  Caroline Cech, Malia McDonald, and Payton Apiki: Reducing food waste across the UH Mānoa campus. Andrew Gibbons, Kiana Davis, Emilee Wong: Increasing native & naturalized plant diversity in urban environments

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CTAHR is in the business of benefiting Ag across the state, helping commercial and individual growers, improving collaboration among stakeholders, and advancing science-based discoveries for everyone. As the contribution of specialty crops – vegetables, fruits, tree nuts, dried fruits, horticulture, nursery crops, floriculture, seed crops, and certified organics – continues to increase in Hawaiʻi’s diversified agriculture economy, so has interest among local growers and Ag-related organizations.

To help guide CTAHR in allocating research and educational resources, a new survey is being conducted by Amjad Ahmad of Extension that will map the types and locations of all specialty crop work conducted by CTAHR.

Your contribution is highly appreciated. Please click the link and complete the survey today.

Photo by Kalani Matsumura, Oʻahu Extension

It may not grab headlines the way Covid has, but obesity is one of the most serious public health problems of the 21st century. More than 600 million adults and 100 million children in 200 countries are considered obese. There are very few safe pharmaceutical interventions, but in a new study from the Dept. of Molecular Biosciences and BioEngineering, researchers have taken a small yet solid step toward developing a natural supplement that could reduce obesity. In the world of natural products, dihydromyricetin (DHM), also called ampelopsin, is known to exert antidiabetic effects. However, the biochemical target of this isolate from the herbal plant Ampelopsis grossedentata is unknown. For this study, the primary goal of principal investigator Qing Li was to identify that biochemical target.

The team, which included C.Y. Hu of the Dept. of Human Nutrition, Food and Animal Sciences, as well as several MBBE students and visiting scholars to CTAHR, was successful and found that the chemical DHM can reduce lipid droplet formation in adipocytes. They also found DHM has direct interaction with a protein called “78-kDa glucose-regulated protein” (GRP78) – the object of their search.

“It was crucial to identify the biochemical target of DHM, and show how DHM is able to reduce lipid droplet formation in 3T3-L1 cells through a mode of action that is plausibly associated with direct interactions between GRP78 and DHM,” says Qing. “Now we can be elucidating GRP78’s physiological function and therapeutic value.”

He adds, “It is quite exciting because the work shows how ampelopsin works as an anti-obesity agent, and is a step forward in determining potential applications of DHM as an anti-obesity agent. This study brings us a step closer to further development of this natural supplement in the clinical setting for combating obesity.”

Read the full study, “Dihydromyricetin imbues anti-adipogenic effects on 3T3-L1 cells via direct interactions with 78-kDa glucose regulated protein,” which appears in the latest issue of the Journal of Nutrition.

For her senior Food Science Capstone project, Trisha Nagasawa has baked up an interesting new treat: breadfruit shortbread cookies. The purpose of the study is to see if a tasty and well-liked product can be made utilizing breadfruit flour. Today, 12:00-3:00 p.m. in AgSci 223, you are invited to stop by, taste a sample cookie, fill out a survey, and help Trisha fulfill her project. Now that’s what I call a Win Win! To reserve a preferred time period, visit here. For questions, contact Trisha. Please note, the cookies contain eggs and dairy.

New funding that aims to coordinate the Supplemental Nutrition Assistance Program (SNAP) with other programs in combatting childhood hunger includes a grant for CTAHR’s Children’s Healthy Living Center of Excellence (CHL). Share Our Strength’s No Kid Hungry campaign, with support from the American Public Human Services Association, will invest nearly $2 million with six SNAP agencies, including Hawaiʻi. The initial goal is to track trends in co-enrollment, identify the characteristics of vulnerable populations that don’t enroll in eligible programs, and guide future programs and policies. Ultimately, the initiative hopes to streamline policy, programs, and resources that impact children and families.

During the 18-month project, CHL will provide technical assistance in data integration and analytics. Following the grant period, CHL will continue to help link data systems and evaluate existing nutrition programs. The project is rooted in the ‘Ohana Nui framework, which seeks to end intergenerational poverty by addressing the needs of multigenerational households.

“This grant helps us form an important collaboration for coordinating data systems on food, nutrition and health-related programs,” says Rachel Novotny of CHL and the Dept. of Human Nutrition, Food and Animal Sciences. “This will enhance program efficiency and effectiveness for Hawaiʻi’s children and families.”