CTAHR NEWS
5/4/2021 11:00 AM - 1:30 PM

NREM 494 Senior Capstone Project Presentation

We invite you to join us Tuesday, May 4, 2021 11:00 AM - 1:30 PM online for the NREM 494 Senior Capstone Project Presentations (Zoom link below)!  The poster showing each of the presenters and titles for the May 4 presentations.
 
Meeting ID: 389 871 7718
Password: Meeting
 



 
4/28/2021 5:30 PM - 7:30 PM

NREM 601, Student community meeting

  Come see the work of University of Hawaiʻi Natural Resources and Environmental Management present their collaborative research with Mālama Maunalua and Mālama Puʻuloa as part of NREM 601, Social-Ecological Systems!

 
April 28th, 2021, 5:30 pm
Meeting ID: 968 4059 2963; Passcode: vX7jCd
4/28/2021 9:00 AM - 10:00 AM

L. Perng PhD Proposal Defense

Please join us for Lansing Perng's PhD Proposal Defense. See the attached flyer for presentation information, abstract, and zoom information.

Topic: Putting in Theory Into Practice: Identifying Thresholds in Social-Ecological Systems

Date: April 28, 2021, 9:00 AM - 10:00 AM HST via Zoom

Zoom Link: https://zoom.us/j/99802409329?pwd=Y2w3anUvTXNTaWYxZE9ERTZJYWs1UT09

Meeting ID: 998 0240 9329 Passcode: perng

Committee:
Dr. Kirsten Oleson
Dr. Kirsten Leong
Dr. Elizabeth Madin
Dr. Mehana Vaughan
Dr. Mariska Weijerman

Anti-Obesity Therapy? 19 April 2021

Anti-Obesity Therapy?

MBBE researchers identify a natural, critical biochemical target

It may not grab headlines the way Covid has, but obesity is one of the most serious public health problems of the 21st century. More than 600 million adults and 100 million children in 200 countries are considered obese. There are very few safe pharmaceutical interventions, but in a new study from the Dept. of Molecular Biosciences and BioEngineering, researchers have taken a small yet solid step toward developing a natural supplement that could reduce obesity. In the world of natural products, dihydromyricetin (DHM), also called ampelopsin, is known to exert antidiabetic effects. However, the biochemical target of this isolate from the herbal plant Ampelopsis grossedentata is unknown. For this study, the primary goal of principal investigator Qing Li was to identify that biochemical target.

The team, which included C.Y. Hu of the Dept. of Human Nutrition, Food and Animal Sciences, as well as several MBBE students and visiting scholars to CTAHR, was successful and found that the chemical DHM can reduce lipid droplet formation in adipocytes. They also found DHM has direct interaction with a protein called “78-kDa glucose-regulated protein” (GRP78) – the object of their search.

“It was crucial to identify the biochemical target of DHM, and show how DHM is able to reduce lipid droplet formation in 3T3-L1 cells through a mode of action that is plausibly associated with direct interactions between GRP78 and DHM,” says Qing. “Now we can be elucidating GRP78’s physiological function and therapeutic value.”

He adds, “It is quite exciting because the work shows how ampelopsin works as an anti-obesity agent, and is a step forward in determining potential applications of DHM as an anti-obesity agent. This study brings us a step closer to further development of this natural supplement in the clinical setting for combating obesity.”

Read the full study, “Dihydromyricetin imbues anti-adipogenic effects on 3T3-L1 cells via direct interactions with 78-kDa glucose regulated protein,” which appears in the latest issue of the Journal of Nutrition.

Taste Test TODAY 19 April 2021

Taste Test TODAY

Try some breadfruit cookies 12:00-3:00 THIS AFTERNOON and support a FSHN capstone project

For her senior Food Science Capstone project, Trisha Nagasawa has baked up an interesting new treat: breadfruit shortbread cookies. The purpose of the study is to see if a tasty and well-liked product can be made utilizing breadfruit flour. Today, 12:00-3:00 p.m. in AgSci 223, you are invited to stop by, taste a sample cookie, fill out a survey, and help Trisha fulfill her project. Now that’s what I call a Win Win! To reserve a preferred time period, visit here. For questions, contact Trisha. Please note, the cookies contain eggs and dairy.

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